Healers & Therapists News

Healers & Therapists News from June Meagher of AAMARHealing brings you the latest news from sources such as the BBC Health pages as well as the Green Med Info pages and Science Daily, we will be adding more news feeds shortly. Join the conversations on our LinkedIn group which has over 18,000 healers and therapists from around the globe and discover even more news and tips. If you have any news you would like to add to our website, please contact me and I can add it to our blog.

 

    • BBC News - Health
    • GreenMedInfo
    • Latest Science News -- ScienceDaily

    Delaying second Pfizer doses to give more people their first is "difficult to justify", says BMA. Read more

    Evidence suggests the variant that emerged in the UK may be more deadly as well as faster-spreading. Read more

    Inadequate PPE and a new variant may be putting the lives of nurses at risk, says nursing union. Read more

    Around one in 10 patients admitted to intensive care is now being sent to a different hospital. Read more

    The UK's chief medical adviser warns that "a very small change and it could start taking off again". Read more

    A special unit set up by the Crown Office is looking into Covid deaths involving 474 care homes across Scotland. Read more

    Doctors say people should buy a pulse oximeter to monitor their oxygen levels at home. Read more

    They say the devices, which are used in local councils, have a key role to play in the battle against Covid. Read more

    Around 200 vaccines are being given every minute, the health secretary tells the Commons. Read more

    Researchers warn that unless something changes, hospitals will continue facing significant pressure. Read more

    More work is needed to understand its benefits in schools in England given the new variant, health officials say. Read more

    Delays to smear tests in lockdown prompt cervical cancer charities to call for home-testing kits. Read more

    Some people who need urgent help appear to be staying away, as in the first peak, say researchers. Read more

    Services and waiting times must improve at the NHS's child gender-identity service, inspectors say. Read more

    The vaccines will be offered to existing high-priority groups and hospital staff on night shifts. Read more

    The BBC's James Cook returns to Monklands Hospital eight months on to find the staff struggling against the odds. Read more

    Some 10% of the UK population is showing signs of recent infection, a doubling since October, says ONS. Read more

    A hospital apologises to Rachael Foley after she underwent a hysterectomy following the error. Read more

    There is some evidence that the new UK variant may be more deadly, says PM Boris Johnson. Read more

    Some of those leading the nation's vaccination effort have told of their experiences. Read more

    The world's first coronavirus quarantine began in Wuhan a year ago - how has China changed since then? Read more

    Israel is likely to be the first country to see an impact from vaccination - but it is still too early. Read more

    Ambulance service staff in London explain the unique pressures of working during a pandemic. Read more

    Cancer patient Luke Grenfell-Shaw completes the first part of his round-the-world challenge. Read more

    One doctor tells her story of battling the pandemic alone in Yemen after her colleagues fled. Read more

    Meet the artists shaping graphic medicine - a genre of comics focused on the experience of living with mental illness. Read more

    Clusters of deaths in the first wave unexpectedly showed up in rural parts of Wales. Read more

    Christmas gatherings were cut back but was there still an impact on Covid cases? Read more

    Everyone has heard about doctors and nurses catching Covid-19 but cleaners and porters have been worse hit. Read more

    The risks of catching Covid indoors are well-known, but what are the chances of being infected outdoors? Read more

    A therapist who arranges free mental health help for NHS workers says many are at "breaking point". Read more

    People around the UK must now wear face coverings in many public places, but what are the rules? Read more

    Two of the three approved Covid vaccines are being rolled out across the UK, so when might you get one? Read more

    People across the country are being urged to "double down" and stick to the lockdown rules. Read more

    Explore the data on coronavirus in the UK and find out how many cases there are in your area. Read more

    As restrictions change across the country, how should more vulnerable people keep themselves safe? Read more

    What is it like to have the coronavirus, how will it affect you and how is it treated? Read more

    Some people across the UK have been able to form "support bubbles" or "extended households". Read more

    What are the tests for coronavirus, who are they for and how do they work? Read more

    A new cough, fever and change in smell or taste are the key symptoms that mean you may have coronavirus. Read more

    - greenmedinfo

    PMID:  J Exp Clin Cancer Res. 2021 Jan 19 ;40(1):34. Epub 2021 Jan 19. PMID: 33468157 Abstract Title:  Vitamin C sensitizes BRAFthyroid cancer to PLX4032 via inhibiting the feedback activation of MAPK/ERK signal by PLX4032. Abstract:  BACKGROUND: BRAFV600E mutation is the most common mutation in thyroid cancer. It strongly activates MAPK/ERK pathway and indicates an invasive subtype of thyroid cancer. PLX4032 is a selective oral inhibitor of the BRAFV600 kinase although with limited effect in treating this panel of thyroid cancer, due to the feedback activation of MAPK/ERK as well as PI3K/AKT pathways. It was investigated that Vitamin C plays a positive role in inhibiting these pathways in thyroid cancer. However, whether Vitamin C could enhance the antitumor effect of PLX4032 remains largely unclear.METHODS: The antitumor efficacy of combination therapy with PLX4032 and Vitamin C on BRAFthyroid cancer cell was assessed by the MTT assay, EdU assay and colony formation, Chou-Talalay way was employed to analyze the synergistic effect. Flow cytometry were employed to assess cells' apoptosis and cell cycle arrest in response to combination therapy. Xenograft models were used to test its in vivo antitumor activity. Western blot and IHC were applied to investigate the mechanism underlying synergistic effect.RESULTS:… Read more

    - greenmedinfo

    PMID:  BMJ Glob Health. 2021 01 ;6(1). PMID: 33472840 Abstract Title:  Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis. Abstract:  Acute respiratory tract infections (ARIs) are a leading cause of ill-health and death globally. Individual or multiple micronutrients have been shown to modulate immune function and affect the risk and severity of a number of infectious diseases. We systematically reviewed the evidence on the impact of micronutrient supplements to reduce the occurrence of ARIs and shorten the duration of ARI symptoms among adults. Random effects meta-analyses were conducted to estimate the pooled effects of vitamin D, vitamin C, zinc and multiple micronutrient supplementation (MMS) on the occurrence of ARIs and the duration of ARI symptoms. Vitamin D supplementation reduced the risk of ARI (risk ratio (RR)=0.97; 95% CI 0.94 to 1.00; p=0.028) and shortened the duration of symptoms (per cent difference: -6% (95% CI -9% to -2%; p=0.003)). The RR of vitamin D to prevent ARI was farther from the null when diagnosis was based on clinical diagnosis or laboratory testing, compared with self-report and when the loading dose wasread more Read more

    - greenmedinfo

    PMID:  Diabetes Care. 2021 Feb ;44(2):618-630. PMID: 33472962 Abstract Title:  Effects of Vitamin C Supplementation on Glycemic Control and Cardiovascular Risk Factors in People With Type 2 Diabetes: A GRADE-Assessed Systematic Review and Meta-analysis of Randomized Controlled Trials. Abstract:  BACKGROUND: Evidence suggests that vitamin C supplementation could be a potential therapy in type 2 diabetes. However, its effectiveness and evidence quality require further evaluation.PURPOSE: To investigate the efficacy of oral vitamin C supplementation in improving glycemic control, cardiovascular risk factors, and oxidative stress in people with type 2 diabetes.DATA SOURCES: Databases (PubMed, Embase, Scopus, Cochrane Library) and clinical trial registries were searched for randomized controlled trials up to 8 September 2020.STUDY SELECTION: Trials in adults with type 2 diabetes were included. Trials were excluded if supplements were not exclusive to vitamin C and ifread more Read more

    - greenmedinfo

    PMID:  Oncology. 1997 Jan-Feb;54(1):19-22. PMID: 8978587 Abstract Title:  'Spontaneous' regression of advanced leiomyosarcoma of the urinary bladder. Abstract:  A case of advanced leiomyosarcoma of the urinary bladder is reported in a 25-year old man who, in a short time, experienced a complete 'spontaneous' regression of his fatal illness. He first presented with severe haemoperitoneum resulting from an unresectable bleeding tumour of the urinary bladder. Debulking surgery was performed, followed by salvage chemotherapy. Histological and ultrastructural examinations of the tumour confirmed a poorly differentiated leiomyosarcoma. The residual disease failed to respond to salvage chemotherapy, but regressed 'spontaneously' 5 months after cessation of therapy. The patient is alive without evidence of disease 51 months after the diagnosis. This remarkable phenomenon and relatively long survival in a poor-risk leiomyosarcoma of the urinary bladder has never been reported previously. read more Read more

    - greenmedinfo

    PMID:  J Dermatol Surg Oncol. 1990 Nov ;16(11):1039-42. PMID: 2246409 Abstract Title:  Complete spontaneous regression of multiple basal cell carcinomas in the basal cell nevus syndrome: the possible role of transepithelial elimination. Abstract:  A 36-year-old Latin American man with the basal cell nevus syndrome had multiple, soft, hairless, depressed scars of the face, scalp, neck, and back, ranging in size from 0.3 x 0.5 cm to 3.5 x 3.9 cm. These areas had never been treated and previously were sites of basal cell carcinomas that underwent complete spontaneous regression 4-5 years from the date of onset. Pathology of these spontaneously regressed sites was consistent with the criteria established by Curson and Weedon (1979). Type III transepithelial elimination was demonstrated for a basal cell carcinoma. Type III transepithelial elimination may play a role in the spontaneous regression of basal cell carcinomas. read more Read more

    - greenmedinfo

    PMID:  Med Clin (Barc). 1990 Sep 15 ;95(8):306-8. PMID: 2283912 Abstract Title:  [Spontaneous tumor regression. Report of 2 cases]. Abstract:  Two cases of spontaneous tumor regression (STR) occurring in a patient with non Hodgkin lymphoma and in another patient with squamous carcinoma of the lung are presented. Both cases fulfill the criteria of STR defined by Everson and Cole. Recent results obtained in basic and clinical studies have indicated that immunological mechanisms could play an important role in STR. The mediator effects more frequently referred are: 1) generation of antineoplastic cytotoxic cells; 2) production of immunoregulatory cytokines by lymphocytes and monocytes, and 3) possible cross reaction between tumor and bacterial antigens. These mechanisms of action are discussed in relation to the presented cases. read more Read more

    - greenmedinfo

    PMID:  Clin Oncol (R Coll Radiol). 1991 Jan ;3(1):46-8. PMID: 2001342 Abstract Title:  A case of spontaneous regression of metastatic testicular teratoma. Abstract:  We report the apparently spontaneous regression of metastatic disease in a young man who had previously undergone orchidectomy for a primary testicular teratoma. Serial serum tumour marker estimations revealed a sharp rise followed by a spontaneous decline in levels in a patient who had requested that chemotherapy be deferred for personal reasons. read more Read more

    - greenmedinfo

    PMID:  Cancer. 1980 Jun 1 ;45(11):2908-12. PMID: 7379022 Abstract Title:  Spontaneous regression of metastatic testicular carcinoma in a patient with bilateral sequential testicular tumor. Abstract:  Spontaneous regression of metastatic neoplasia is rate. A review of previously reported spontaneous regressions of testicular cancer indicates that in no case has such a patient had a prior, concurrent, or subsequent contralateral tumor. The case presented is unusual because it is the first instance of bilateral sequential testicular cancer in which spontaneous regression of metastases from one of the tumors has been noted. Together with a previous report of a spontaneous regression of testicular cancer which occurred only after a second orchiectomy, the present case suggests the possibility of hormonal modulation of tumor growth. read more Read more

    - greenmedinfo

    PMID:  Crit Rev Oncol Hematol. 2016 Feb ;98:122-36. Epub 2015 Nov 9. PMID: 26597016 Abstract Title:  Meta-analysis of regression of advanced solid tumors in patients receiving placebo or no anti-cancer therapy in prospective trials. Abstract:  BACKGROUND: A meta-analysis of prospective trials systematically investigated regression of advanced solid tumors in patients receiving placebo or no anticancer therapy to inform on spontaneous regressions.PATIENT AND METHODS: Arms of randomized controlled trials (RCTs) of metastatic solid tumors receiving placebo or no anti-cancer therapy were used. Statistical analyses were conducted to calculate the overall response rate (ORR) and to detect differentials based on histology, progression at baseline and prior therapies.RESULTS: A total of 7676 patients were evaluable from 61 RCTs evaluating 18 solid tumors. The ORR was 1.95% (95% CI: 1.52-2.48%). There was no significant effect of histology (p=0.110), baseline progressive disease (p>0.20) or the line of therapy (p>0.20) on ORR.CONCLUSIONS: Spontaneous regressions are seen across all advanced solid tumors. Some malignancies demonstrated higher rates of spontaneous regressions and may be relatively immunotherapy responsive. read more Read more

    - greenmedinfo

    PMID:  Radiat Med. 2006 Feb ;24(2):139-42. PMID: 16715676 Abstract Title:  A case of spontaneous regression of hepatocellular carcinoma with multiple lung metastases. Abstract:  Spontaneous regression of hepatocellular carcinoma (HCC) is a rare phenomenon. We present herein the case of a patient with hepatocellular carcinoma with multiple lung metastases in whom malignancy spontaneously regressed after taking Pheliinus linteus Mycelium. A 79-year-old man consulted our hospital complaining of epigastric discomfort. Abdominal MRI and CT revealed a 3 cm diameter tumor in the liver, and chest CT showed numerous nodular lesions. The levels of alpha-fetoprotein (AFP) and protein induced by vitamin K deficiency or antagonist-II (PIVKA-II) were very high. We diagnosed HCC with multiple lung metastases, and no therapy was performed. Independently he took exact from Phellinus linteus Mycelium for one month, and 6 months later the tumors appeared to be in complete regression. The mechanism underlying this intriguing phenomenon remains unknown. read more Read more

    - greenmedinfo

    PMID:  Tumori. 2014 Jul-Aug;100(4):144e-7e. PMID: 25296606 Abstract Title:  Metastatic melanoma with spontaneous regression, psoriasis and HLA-Cw6: case report and a hypothesis to explore. Abstract:  Spontaneous regressions of metastatic melanoma are rare, but several cases have been described in the literature. Although the mechanism of the phenomenon is not well understood, it is postulated that an activation of the immune system is behind it. Here we report the case of a patient with metastatic melanoma that, without any treatment, regressed spontaneously. The patient presented psoriasis (a disease of the skin related with autoimmunity) linked with HLA-Cw6. We review the literature and hypothesize with the possible relationship between psoriasis, HLA-Cw6 and the spontaneous regression. read more Read more

    - greenmedinfo

    PMID:  Klin Monbl Augenheilkd. 2002 May ;219(5):387-9. PMID: 12094325 Abstract Title:  [Spontaneous regression of an eyelid tumour]. Abstract:  BACKGROUND: The differential diagnosis of eyelid tumours is often a challenging task. A correct anamnesis can be very important for the further treatment plan.CASE REPORT: A 73-year-old female patient presented with a tumour of her left lower eyelid which occurred two months ago. The suspected clinical diagnosis of a basal cell carcinoma was confirmed. After one month the patient was admitted for tumour excision and eyelid reconstruction, but the tumour showed marked regression. Because of a now clinically suspected keratoacanthoma, we decided to observe the tumour and cancelled surgery. Fourteen days later there was no tumor visible on her left lower eyelid. It seemed to be a spontaneous regression of a keratoacanthoma.CONCLUSIONS: If there is a short case history of a rapidly growing eyelid tumour one should also consider keratoacanthoma as differential diagnosis. In suspected cases initial observation and control can save the patient from extended excision and eyelid reconstruction. However, an unnecessary delay of treatment due to prolonged observation without any signs of regression should be avoided. Unclear situations require a diagnostic excision to exclude a squamous cell carcinoma or basal… Read more

    - greenmedinfo

    PMID:  Hepatogastroenterology. 2001 Nov-Dec;48(42):1740-2. PMID: 11813613 Abstract Title:  Spontaneous regression of hepatocellular carcinoma--a case report. Abstract:  We report a 72-year-old man with hepatocellular carcinoma, which showed spontaneous regression. He was diagnosed as having chronic hepatitis type C five years before admission. In January 1998, a liver mass was found by ultrasonography. In February, computed tomography showed a low-density mass, 3.5 cm in diameter in the S5 region. Although liver biopsy was not performed, findings obtained by computed tomography and ultrasonography indicated that the tumor was hepatocellular carcinoma. The levels of alpha-fetoprotein and PIVKA (protein induced by vitamin K antagonist)-II were increased to 1000 ng/mL and 2000 mAU/mL, respectively. The patient was admitted to our hospital in March 1998. At the time, the size of liver mass was reduced to 2.5 cm in diameter on computed tomography, and the tumor markers, alpha-fetoprotein and PIVKA-II, spontaneously decreased to the normal range. We considered that hepatocellular carcinoma of this patient regressed spontaneously. Because it was hard to exclude the possibility that the mass contained residual malignant cells, we resected the mass on April 28, 1998. Microscopically, the resected mass did not contain any malignant cells. The parenchyma surrounding tumor necrosis, which is reflected… Read more

    - greenmedinfo

    PMID:  J Child Neurol. 1999 Jun ;14(6):352-6. PMID: 10385841 Abstract Title:  Spontaneous partial regression of low-grade glioma in children with neurofibromatosis-1: a real possibility. Abstract:  At the age of 41 and 31 months, respectively, a boy and a girl affected by neurofibromatosis-1 were diagnosed with a visual pathway glioma during surveillance contrast-enhanced head magnetic resonance imaging (MRI). In the first child, the initial MRI showed that the entire optic chiasm, the intracranial tract of the left optic nerve, and hypothalamus were grossly enlarged and enhanced in the post-gadolinium T1-weighted images. Ten months later, the hypothalamic component of the lesion had regressed markedly and there were no more areas of contrast enhancement. In the second child, the initial MRI showed that the optic chiasm, the right optic tract, and geniculate body were enlarged and enhanced after gadolinium injection. At 6-month follow-up, the MRI showed that the right optic tract and the anterior aspect of the optic chiasm decreased in size and the contrast enhancement of the entire lesion was reduced dramatically. These findings, as indicated by other similar reports, confirm that spontaneous regression of visual pathway glioma is a rare but real possibility in children with neurofibromatosis-1. Therefore, clinicians need to… Read more

    - greenmedinfo

    PMID:  J Craniomaxillofac Surg. 2014 Oct ;42(7):1536-9. Epub 2014 May 9. PMID: 24958155 Abstract Title:  Spontaneous remission of a squamous cell carcinoma of the floor of the mouth. Abstract:  Spontaneous remission is a rare, but well recognized event in oncology. Certain tumours, such as melanomas, hypernephromas and neuroblastomas, are known for showing spontaneous regression. Similarly, spontaneous regression of oral lymphomas, as well as oropharyngeal and recurrent tongue carcinomas, has been reported. Here, we present a novel case of a patient with a primary squamous cell carcinoma on the floor of the mouth whose tumour regressed spontaneously in three months, without any treatment. We also review of the literature on the spontaneous remission of oral cancer and discuss possible mechanisms for this phenomenon. read more Read more

    - greenmedinfo

    PMID:  Rev Med Univ Navarra. 1990 Jul-Sep;34(3):141-2. PMID: 2151656 Abstract Title:  [Spontaneous tumor regression in a patient with metastatic gastric cancer. Communication of an additional case]. Abstract:  A new case of spontaneous tumor regression in a patient with a metastatic gastric carcinoma, associated to an infectious abscess in the abdominal wall is presented. Streptococcus faecalis and Staphylococcus aureus were isolated in the abscess. This interesting case is the third patient that fulfils spontaneous regression criteria associated to infection identified at the University Clinic of Navarra. read more Read more

    - greenmedinfo

    PMID:  Ann Dermatol Venereol. 2010 Jun-Jul;137(6-7):464-7. Epub 2010 Jun 4. PMID: 20620577 Abstract Title:  [Long-term survival and spontaneous tumor regression in stage IV melanoma: possible role of adrenalectomy and massive tumor antigen release]. Abstract:  BACKGROUND: Mean survival for stage IV melanoma patients is 6 to 8 months. Long-term survival is rare and spontaneous regression even more unusual.PATIENTS AND METHODS: A 46-year-old woman underwent amputation of the left thumb for subungual melanoma in 1997. In 2002, lobectomy was performed for a single pulmonary metastasis. In June 2006, a seemingly isolated adrenal metastasis was detected, and was rapidly complicated by acute abdominal symptoms due to metastatic rupture that required emergency adrenalectomy. During surgery, peritoneal metastases were observed macroscopically and confirmed histologically. One month later, then every six months until July 2009, clinical and laboratory tests, and in particular positron emission tomodensitometry (PET) scans, revealed no further tumoural lesions. No treatment was given. Screening for signs of autoimmunity revealed isolated appearances of anticardiolipin antibodies starting in June 2006.DISCUSSION: This rare case suggests the existence of specific factors resulting in tumour control. The favourable prognostic value of autoimmune signs has been discussed in stage III and IV melanoma. A number of studies have also… Read more

    - greenmedinfo

    PMID:  Ultraschall Med. 1991 Feb ;12(1):41-4. PMID: 2057755 Abstract Title:  [Spontaneous regression of liver metastases in neuroendocrine tumors of the abdomen]. Abstract:  In six patients with hepatically metastasised gastrointestinal tumours of neuro-endocrinal origin, including one each islet cell carcinoma and gastrinoma of the pancreas, one cloacogenic carcinoma (a rare type of anal cancer), and three carcinoid tumours of the small bowel, spontaneous liquefaction inside echogenic liver metastases was demonstrated by ultrasound. The hepatic lesions were classified as being of"bull's-eye-"shape without"badge"pattern. Chemotherapy had no effect on their ultrasonographic imaging. With regard to our observations, liquefying processes were far more common in these well-differentiated tumour metastases than in poorly differentiated fast-proliferating malignancies (about 1:40). Assessment of liquefaction, however, has obviously no influence on the prognosis of progress speed. Ultrasonographic differential diagnosis includes focal inflammatory disease of the liver, if there is no evidence of a primary tumour. read more Read more

    - greenmedinfo

    PMID:  J Neurosurg. 2010 Jan ;112(1):158-62. PMID: 19499981 Abstract Title:  Spontaneous regression of vestibular schwannomas after resection of contralateral tumor in neurofibromatosis Type 2. Abstract:  The authors report on 2 patients with bilateral vestibular schwannomas (VSs) who underwent unilateral surgical tumor removal. One patient was followed up for 4 years, the other for 9; in both cases, the contralateral VS regressed markedly without any additional treatment during the follow-up period. Serial MR imaging was performed to monitor the untreated tumor, which in both cases involved the only hearing ear. The tumors were assessed volumetrically. The contralateral tumors appeared to enlarge mildly at initial follow-up and then, with no treatment, regressed (to 23% of the original maximum volume in Case 1 and to 15% of the original maximum in Case 2). The largest posterior fossa diameter decreased from 30.1 mm to 18.6 mm in Case 1 over 4 years and from 27 mm to 16 mm over 8 years in Case 2. Hearing declined only mildly during follow-up in both patients. These cases demonstrate the first well-documented, long-term, spontaneous VS regressions in patients with neurofibromatosis Type 2. They underline the importance of careful observation of VS involving the only hearing ear… Read more

    - greenmedinfo

    PMID:  Int J Urol. 2008 Mar ;15(3):265-6. PMID: 18304227 Abstract Title:  Spontaneous regression of pulmonary metastases from testicular embryonal carcinoma. Abstract:  A 22-year-old man was referred to our hospital for a lung tumor on a chest X-ray examination. Computed tomography of the chest revealed multiple coin lesions. Magnetic resonance imaging of the left testis showed an 8-mm tumor that was hard and palpable. Testicular tumor with lung metastasis was diagnosed and orchiectomy was performed. The histopathological diagnosis was embryonal carcinoma with infiltration of histiocytes. Four days after the operation, a chest X-ray showed a remarkable regression of the lung tumors. Chemotherapy was not performed because the metastatic lesions continued to regress spontaneously. Six months later, no tumor was observed on computed tomography images of the lungs. read more Read more

    - greenmedinfo

    PMID:  J Med Case Rep. 2015 Sep 17 ;9:217. Epub 2015 Sep 17. PMID: 26377170 Abstract Title:  Spontaneous regression of non-small cell lung cancer after biopsy of a mediastinal lymph node metastasis: a case report. Abstract:  INTRODUCTION: Spontaneous regression of cancer is defined as a complete or partial, temporary or permanent disappearance of tumor in the absence of specific therapy. With only a few cases reported, spontaneous regression is extremely rare in primary lung cancer. Regarding spontaneous regression in lung cancer, recent investigations revealed the role of immunological mechanisms, thus indicating potential treatment options by specific immunotherapy in the future.CASE PRESENTATION: A 76-year-old Caucasian man with progressive dyspnea presented to our hospital. A computed tomography scan revealed a tumor mass in the upper lobe of his right lung and enlarged mediastinal lymph nodes. A biopsy of a paratracheal lymph node by mediastinoscopy disclosed metastatic lung cancer. By immunohistochemical findings the tumor was classified as large cell carcinoma. Diagnosed with clinical stage IIIA non-small cell lung cancer, a neoadjuvant therapy concept was indicated. However, before starting chemoradiation, a computed tomography scan showed a regression of both the tumor mass in the upper lobe of his right lung and the mediastinal lymphadenopathy.… Read more

    - GMI Research Group

    Findings highlight the pro- or anti-inflammatory potential of the food you eat, particularly in promoting or fighting cardiovascular disease and stroke Read more

    - GMI Research Group
    Eat More Yellow Veggies, Coffee to Zap Inflammation, Heart Disease Risk

    This article is copyrighted by GreenMedInfo LLC, 2021Visit our Re-post guidelines Findings highlight the pro- or anti-inflammatory potential of the food you eat, particularly in promoting or fighting cardiovascular disease and stroke. Yellow vegetables, green leafy vegetables, coffee, tea and even red wine appear particularly beneficial Certain diets have been shown to increase inflammation in your body, which then sets the stage for heart disease and stroke later in life. Yet there are also diets that can save the day, including those rich in yellow vegetables, red wine and coffee, according to research published in the Journal of the American College of Cardiology in November 2020.[i]read more Read more

    - greenmedinfo

    PMID:  Lung Cancer. 2015 Jan ;87(1):73-6. Epub 2014 Nov 3. PMID: 25468200 Abstract Title:  Spontaneous regression of small cell lung cancer combined with cancer associated retinopathy. Abstract:  Spontaneous regression (SR) is defined as the complete or partial disappearance of disease without anticancer treatments. We report a case of SR of small cell lung cancer (SCLC) combined with cancer associated retinopathy (CAR). A 65-year-old woman was admitted to our hospital to examine abnormal shadows of the lung with visual loss. She was diagnosed with SCLC associated with CAR. Subsequent chest X-ray and CT scan showed partial regression of both primary tumor and lymph node metastasis without anticancer treatment. Recoverin antigen was present on the tumor cells and anti-recoverin antibody was observed in the patient's serum. Activation of recoverin-specific antitumor cytotoxic T lymphocyte (CTL) was observed in this patient. SCLC was considered to reduce spontaneously by the activation of recoverin-specific antitumor CTL. To the best of our knowledge, this is the first report of SR in SCLC combined with CAR. read more Read more

    - greenmedinfo

    PMID:  Intern Med. 2013 ;52(19):2249-52. Epub 2012 Mar 1. PMID: 24088761 Abstract Title:  Small-cell lung cancer exhibiting spontaneous regression. Abstract:  A 56-year-old woman was admitted to our hospital because a chest X-ray and thoracic computed tomography (CT) scan revealed a heterogeneous tumor in the middle mediastinum during a visit to a nearby clinic for a consultation regarding a persistent cough and body weight loss. However, the tumor spontaneously decreased on thoracic CT performed on admission. Subsequently, a biopsy of the tumor using video-assisted thoracoscopy was performed. The pathological findings disclosed the tumor to be small-cell lung cancer with infiltration of CD8-positive T-cells exhibiting spontaneous regression. Cell-mediated immunity, including CD8-positive T-cells, may have relevance to the spontaneous regression of malignant tumors. read more Read more

    - greenmedinfo

    PMID:  Exp Neurol. 2004 Dec ;190(2):478-85. PMID: 15530886 Abstract Title:  Spontaneous regression of experimental gliomas--an immunohistochemical and MRI study of the C6 glioma spheroid implantation model. Abstract:  OBJECTIVE: The orthotopic C6 glioma spheroid implantation model has been used to examine factors of neoangiogenesis, growth factor release, and protease expression as well the effect of antitumor agents. The present study systematically investigates the long-term course of orthotopically implanted C6 spheroid gliomas.METHODS: Reaggregated C6 spheroid tumors were implanted into the forebrain of 48 male Sprague-Dawley rats (32 immunocompetent, 16 thymectomized). The animals were examined by MRI at postoperative day (POD) 7, 14, 21, 28, 32, 45, 60, and 70. The MRI protocol included a T2-w and T1-w SE sequence before and after application of contrast medium and a CISS 3D sequence for volumetry. A total of six animals were selected after each MR exam from both groups and sacrificed for HE light microscopy and CD8+ T-lymphocyte, ED1+ macrophage, CD31+ endothelial cell immunohistochemistry.RESULTS: The tumors progressed to reach a maximum volume on day 28: 0.23 +/- 0.05 ml in the thymectomized and 0.16 +/- 0.021 ml in the immunocompetent group. Tumors then consistently regressed to vanish completely by POD 70. The influx of… Read more

    - greenmedinfo

    PMID:  Arch Ophthalmol. 2001 Apr ;119(4):516-29. PMID: 11296017 Abstract Title:  Spontaneous regression of optic gliomas: thirteen cases documented by serial neuroimaging. Abstract:  OBJECTIVE: To demonstrate spontaneous regression of large, clinically symptomatic optic pathway gliomas in patients with and without neurofibromatosis type 1 (NF-1).METHODS: Patient cases were collected through surveys at 2 consecutive annual meetings of the North American Neuro-Ophthalmology Society (NANOS) and through requests on the NANOSNET Internet listserv. Serial documentation of tumor signal and size, using magnetic resonance imaging in 11 patients and computed tomography in 2 patients, was used to evaluate clinically symptomatic optic pathway gliomas. All tumors met radiologic criteria for the diagnosis of glioma and 4 patients had biopsy confirmation of their tumors. In 3 patients, some attempt at therapy had been made many years before regression occurred. In one of these, radiation treatment had been given 19 years before tumor regression, while in another, chemotherapy had been administered 5 years before signal changes in the tumor. In the third patient, minimal surgical debulking was performed 1 year before the tumor began to shrink.RESULTS: Spontaneous tumor shrinkage was noted in 12 patients. Eight patients did not have NF-1. In an additional patient without NF-1, a signal… Read more

    - greenmedinfo

    PMID:  Pathology. 1975 Apr ;7(2):91-9. PMID: 1153228 Abstract Title:  Spontaneous regression of melanoma. Abstract:  Primary cutaneous melanoma has a tendency to disappear spontaneously. Histologically the active phase is characterized by a dense infiltrate of lymphocytes similar to that seen in spontaneously disappearing naevi. The regression process may continue until the tumour has been completely destroyed, or it may cease when only a part of the tumour has been destroyed. The lymphocytes disappear when the process halts leaving vascular scar tissue with a variable number of pigment-containing phagocytes. As a result of this a certain number of distinctive clinical patterns can be recognized: (1) An inflammatory nodule with or without pigmentation; (2) scarring in the tumour; (3) several foci of melanoma simulating multicentricity; (4) pigmented lesion with a depigmented halo; (5) pigmented scar with surviving melanoma cells; (6) pigmented scar without surviving tumour cells; and (7) metastatic melanoma with no demonstrable cutaneous primary. Only melanomas with a component of superficial spreading type have been found undergoing spontaneous regression. read more Read more

    - greenmedinfo

    PMID:  Pediatr Neurosurg. 2008 ;44(4):324-8. Epub 2008 May 27. PMID: 18504420 Abstract Title:  Spontaneous regression of low-grade gliomas in pediatric patients without neurofibromatosis. Abstract:  OBJECTIVE: Pediatric low-grade gliomas comprise a diverse range of central nervous system tumors, sharing the usual course of a slow progression in growth. In individual cases however, the natural history can be variable, and rarely spontaneous regression has been described. This paper describes factors associated with spontaneous regression.METHODS: A literature review was performed to identify factors associated with spontaneous regression. A unique case is described to contribute to the findings.RESULTS: Low-grade gliomas occurring in association with neurofibromatosis are more likely to spontaneously regress. Only 14 cases of spontaneous regression of low-grade gliomas in patients without neurofibromatosis have been described, and of these, the vast majority regress in association with optic chiasm gliomas. We describe the first documented case of spontaneous regression of a temporal lobe pilocytic astrocytoma in a patient without neurofibromatosis.CONCLUSION: Spontaneous regression of low-grade gliomas can occur for tumors in a diversity of anatomical locations, at varying ages and in both sexes. This may have implications for management. As such, spontaneous tumor regression is an important outcome to be considered for pediatric low-grade gliomas… Read more

    - greenmedinfo

    PMID:  Anticancer Drugs. 2016 Apr ;27(4):269-77. PMID: 26813865 Abstract Title:  Spontaneous regression of tumour and the role of microbial infection--possibilities for cancer treatment. Abstract:  This review deals with the role of microorganisms in spontaneous regression of a tumour. Spontaneous cancer regression is a phenomenon that has been described for many centuries. One of the most well known methods of inducing spontaneous regression of cancer is the application of Coley's toxin (heat-killed Streptococcus pyogenes and Serratia marcescens), which has been used for the successful treatment of sarcomas, carcinomas, lymphomas, myelomas and melanomas. In clinical practice, the use of Bacillus Calmette-Guérin vaccine for the treatment of superficial urinary bladder cancer is the most common instance of the application of microorganisms for the treatment of cancer. This review provides further information on other tested bacteria--Clostridium spp., Bifidobacterium spp., Lactobacillus spp. and Salmonella spp.--in this field of study. Among new age methods, bactofection, alternative gene therapy, combination bacteriolytic therapy and bacteria-directed enzyme prodrug therapy are some of the potential cancer treatment modalities that use microorganisms. We have also provided information about theinterconnection among microorganisms, immune system response, and the possible mechanisms involved in the spontaneous regression of tumours. read more Read more

    Laser beams are used to change the properties of materials in an extremely precise way. However, the underlying processes generally take place at such unimaginably fast speeds and at such a small scale that they have so far eluded direct observation. Researchers have now managed to film, for the first time, the laser transformation of a crystal structure with nanometer resolution and in slow motion in an electron microscope. Read more

    New research shows that non-steroidal anti-inflammatory drugs (NSAIDs) reduced both antibody and inflammatory responses to SARS-CoV-2 infection in mice. Read more

    A new study of 1040 online participants from five western countries explores people's response to the stresses of the escalating pandemic, finding more than 13 percent of the sample had post-traumatic stress disorder (PTSD) related symptoms consistent with levels necessary to qualify for a clinical diagnosis. Read more

    Degradable, bio-based polymers offer options for chemical recycling, and they can be a tool to store and release useful molecules. Scientists have developed a class of sugar-based polymers that are degradable through acid hydrolysis. The researchers also integrated 'cargo' molecules in the polymer, which are designed to split off after polymer degradation. Read more

    In a promising result for the success of vaccines against COVID-19, rhesus macaque monkeys infected with the human coronavirus SARS-CoV-2 developed protective immune responses that might be reproduced with a vaccine. Read more

    Loneliness in adults aged 50 and over during the COVID-19 lockdown was linked to worsening depressive and other mental health symptoms, according to a large-scale online study. Read more

    Astronomers have detected the first Jupiter-like planet without clouds or haze in its observable atmosphere. Read more

    Scientists have miniaturized the optical components required to cool atoms down to a few thousandths of a degree above absolute zero, the first step in employing them on microchips to drive a new generation of super-accurate atomic clocks, enable navigation without GPS, and simulate quantum systems. Read more

    Researchers have found evidence that large ambush-predatory worms -- some as long as two meters -- roamed the ocean floor near Taiwan over 20 million years ago. Read more

    A new collaborative study reveals unexpected insights into how skin exposure to ultraviolet light can worsen clinical symptoms in autoimmune diseases such as lupus. Read more

    A psychology and neuroscience professor has just targeted an early biomarker of the disease. Read more

    A new study of Type 2 diabetes (T2D) in Japanese populations has uncovered a previously uncharacterized genetic variant that puts male carriers at greater risk for the disease, as well as the mechanism by which it does so. The impact of the variant was most pronounced in sedentary men; those with the variant had a 65% greater rate of T2D than sedentary men without it. Read more

    A promising lead halide perovskite is great at converting sunlight to electricity, but it breaks down at room temperature. Now scientists have discovered how to stabilize it with pressure from a diamond anvil cell. The required pressure is well within the reach of industrial manufacturing requirements. Read more

    Researchers have developed an automated way to design customized hardware that speeds up a robot's operation. The system, called robomorphic computing, accounts for the robot's physical layout in suggesting an optimized hardware architecture. Read more

    A study of spitting cobras reveals how a combination of venom components have evolved to create an instantly painful venom, not once, but on three separate occasions. Read more

    How long does immunity to SARS-CoV-2 last following infection? Researchers have uncovered an interesting clue. Their new study suggests that people with severe COVID-19 cases may be left with more of the protective 'memory' T cells needed to fight reinfection. Read more

    Researchers have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences. Read more

    Warnings about misinformation are now regularly posted on Twitter, Facebook, and other social media platforms, but not all of these cautions are created equal. New research from Rensselaer Polytechnic Institute shows that artificial intelligence can help form accurate news assessments -- but only when a news story is first emerging. Read more

    A new global, mathematical modeling study shows that in most cases prioritizing older adults for COVID-19 vaccines saves the most lives. It also found that, in some cases, more lives could be saved and infections prevented if those who've already tested positive step to the back of the line. Read more

    Researchers reveal the kinds of infrastructure improvements that would make the biggest difference in increasing the number of electric cars on the road, a key step toward reducing greenhouse gas emissions from transportation. Read more

    Delivering a minor electric shock into a stream to reveal any fish lurking nearby may be the gold standard for detecting fish populations, but it's not much fun for the trout. Scientists have found that sampling stream water for evidence of the presence of various species using environmental DNA, known as eDNA, can be more accurate than electrofishing, without disrupting the fish. Read more

    If you believe you are capable of becoming the healthy, engaged person you want to be in old age, you are much more likely to experience that outcome, a recent study shows. Read more

    Under FDA emergency-use authorization, doctors successfully resolved COVID-19 in a seriously ill, immunodeficient woman using a very high-neutralizing antibody-titer convalescent plasma from a recovered COVID-19 patient. However, further study suggested that use of convalescent plasma may not be warranted in many cases, for two reasons: 1) titer levels are too low in many convalescent plasmas, and 2) there are high endogenous neutralizing antibody titers already present in COVID-19 patients prior to infusion. Read more

    Researchers have shown that tiny channels between graphene sheets can be aligned in a way that makes them ideal for water filtration. Read more

    Researchers report a comprehensive pilot study on the metabolic effects of full vegan diet on young children. The study found vegan children to have remarkably altered metabolism and lower vitamin A and D status compared to children with no special diet. Read more

    As part of a clinical study, researchers are conducting a thorough and highly precise investigation into the molecular and functional properties of tumors. Their goal is to help physicians to better determine which treatment will best match every patient's cancer and thus be most effective. Read more

    Two out of five individuals delayed or missed medical care in the early phase of the pandemic -- from March through mid-July 2020. Read more

    Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in colon, endometrial, and other cancers. This alternative to complex, multi-step testing workflows can also determine causes of MMR deficiency often missed by current clinical tests. Read more

    Schools are closing again in response to surging levels of COVID-19 infection, but staging randomized trials when students eventually return could help to clarify uncertainties around when we should send children back to the classroom, according to a new study. Read more

    As scientists increasingly rely on eyewitness accounts of earthquake shaking reported through online systems, they should consider whether those accounts are societally and spatially representative for an event, according to a new article. Read more

    Researchers have developed the first comprehensive framework to classify small-cell lung cancer (SCLC) into four unique subtypes, based on gene expression, and have identified potential therapeutic targets for each type in a study. Read more

    Researchers have discovered a new enzymatic function of the Epstein-Barr Virus (EBV) protein EBNA1, a critical factor in EBV's ability to transform human cells and cause cancer. Study provides new indications for inhibiting EBNA1 function, opening up fresh avenues for development of therapies to treat EBV-associated cancers. Read more

    In nature, many things have evolved that differ in size, color and, above all, in shape. While the color or size of an object can be easily described, the description of a shape is more complicated. Researchers have now outlined a new and improved way to describe shapes based on a network representation that can also be used to reassemble and compare shapes. Read more

    Researchers found that stone tools of the type known as 'chopping tools' were used to break open the bones of animals. Tools of this type were used for over two million years. They were found in large quantities at prehistoric sites all over the Old World, but no one understood their exact function. Read more

    Patients with motor dysfunctions are on the rise across Japan as its population continues to age. A researcher has developed a new method of rehabilitation using virtual reality to increase the sense of agency over our body and aid motor skills. Read more

    A working group develops strategies for regeneration of articular cartilage and has found that natural cartilage matrix is suitable as a biomaterial for improved cartilage regeneration. Read more

    With an epitope-based immunization, scientists have described a new vaccination strategy against Staphylococcus aureus. Read more

    Electrical trigger sites in neurons surprisingly change with experience; they are either becoming smaller with increasing number of experiences and, vice versa, they grow larger when less input arrives in the brain. Read more

    Scientists have just shown that the influence of Saturn's satellites can explain the tilt of the rotation axis of the gas giant. Their work also predicts that the tilt will increase even further over the next few billion years. Read more

    The fluttery flight of butterflies has so far been somewhat of a mystery to researchers, given their unusually large and broad wings relative to their body size. Now researchers have studied the aerodynamics of butterflies in a wind tunnel. The results suggest that butterflies use a highly effective clap technique, therefore making use of their unique wings. This helps them rapidly take off when escaping predators. Read more

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